Multidomain Selective Feature Fusion and Stacking Based Ensemble Framework for EEG-Based Neonatal Sleep Stratification


Por: Irfan M., Wang L., Shahid H., Xu Y., Subasi A., Munawar A., Mustafa N., Chen C., Westurlund T., Chen W.

Publicada: 1 ene 2026
Resumen:
Employing a minimal array of electroencephalography (EEG) channels for neonatal sleep stage classification is essential for data acquisition in the Internet of Medical Things (IoMT), as single-channel and edge-based features can reduce data transfer and processing requirements, enhancing cost-effectiveness and practicality. In this paper, we evaluate the efficacy of a single channel and the viability of a binary classification scheme for discerning awake and sleep states and transitions to quiet sleep. For this, two datasets of EEG signals for neonate sleep analysis were recorded from Children's Hospital of Fudan University, Shanghai, comprising recordings from 64 and 19 neonates, respectively. From each epoch, a diverse ensemble of 490 features was extracted through a blend of discrete and continuous wavelet transforms (DWT, CWT), spectral statistics, and temporal features. In addition, we introduced an innovative hybrid univariate and ensemble feature selection approach with multidomain feature fusion, a stacking-based ensemble classifier that outperforms existing work. We achieved 90.37%, 91.13%, and 94.88% accuracy for sleep/awake, quiet sleep/non-quiet sleep, and quiet sleep/awake, respectively. This was corroborated by significant Kappa values of 77.5%, 80.29%, and 89.76%. Using SelectPercentile, we devised three distinct feature selection mechanisms: one using DWT, one with CWT, and another incorporating both spectral and temporal features. Subsequently, SelectKBest was used to determine the most effective features. For our stacked model, we incorporated a trifecta of the ExtraTree model with variable estimators, a Random Forest, and an Artificial Neural Network (ANN) as base classifiers, and for the final prediction phase, ANN was implemented again. The model's performance was evaluated using K-fold and leave-one-subject cross-validation. © 2013 IEEE.

Filiaciones:
Irfan M.:
 Fudan University, Shanghai, China

 University of Turku, Finland

Wang L.:
 Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China

Shahid H.:
 Centre Tecnològic de Telecomunicacions de Catalunya, Spain

Xu Y.:
 Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China

Subasi A.:
 University at Albany, United States

 Effat University, Saudi Arabia

Munawar A.:
 Tianjin University, China

Mustafa N.:
 MetronHK Vision Technology (An Apple Subsidiary), China

Chen C.:
 Fudan University, Human Phenome Institute, Shanghai, China

Westurlund T.:
 Fudan University, Shanghai, China

Chen W.:
 University of Sydney, Australia
ISSN: 21682208
Editorial
Institute of Electrical and Electronics Engineers Inc., 445 HOES LANE, PISCATAWAY, NJ 08855-4141 USA, Estados Unidos America
Tipo de documento: Article
Volumen: 30 Número: 4
Páginas: 2828-2838
WOS Id: 001736042800004
ID de PubMed: 40030895
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